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Javier A. Izquierdo

Assistant Professor of Biology


Degrees

PHD, 2007, Univ Mass Amherst; BSC, 1998, Case Western Reserve Univ


Bio

Research in Dr. Izquierdo's lab focuses on exploring the metabolic diversity of microbial processes and the applications we can derive from them. He utilizes cross-disciplinary approaches incorporating microbiological, ecological, evolutionary, molecular and genomic techniques to 1) understand the contributions of plant microbiomes to the health of their host and 2) discover novel microbial processes for the sustainable production of biofuels and bioproducts from agricultural wastes.

Dr. Izquierdo did his postdoctoral work as a Research Scientist for the DOE-funded BioEnergy Science Center (BESC) at Dartmouth College and North Carolina State University, investigating the diversity and the physiology of thermophilic microbes able to convert cellulose to fuels and chemicals. He obtained his doctorate degree in microbiology investigating the diversity of microbes involved in nitrogen-cycling processes in agricultural soils and the response of these communities to environmental disturbance. Prior to joining Hofstra, Dr. Izquierdo was also active in the industrial sector as Bioenergy Program Manager at the Center of Agricultural and Environmental Biotechnology at RTI International. Dr. Izquierdo holds a B.Sc. in Biology from Case Western Reserve University and a Ph.D. in Microbiology from the University of Massachusetts Amherst. 

PUBLICATIONS

Zurawski, J.V., J.M. Conway, L.L. Lee, H.J. Simpson, J.A. Izquierdo, S. Blumer-Schuette, I. Nookaew, M.W.W. Adams and R.M. Kelly (2015). Comparative analysis of extremely thermophilic Caldicellulosiruptor species reveals common and unique cellular strategies for plant biomass utilization. Appl Environ Microbiol 81(20): 7159-7170

Rooney, E.A., K.T. Rowe, A. Guseva, M. Huntemann, J.K. Han, A. Chen, N.C. Kyrpides, K. Mavromatis, V.M. Markowitz, K. Palaniappan, N. Ivanova, A. Pati, K. Liolios, H.P. Nordberg, M.N. Cantor, S.X. Hua, N. Shapiro, T. Woyke, L.R. Lynd, J.A. Izquierdo (2015). Draft genome sequence of the cellulolytic and xylanolytic thermophile Clostridium clariflavum Strain 4-2a. Genome Announc 3(4): e00797-15

Lee, L.L., J.A. Izquierdo, S.E. Blumer-Schuette, J.V. Zurawski, J.M. Conway, R. W. Cottingham, M. Huntemann, A. Copeland,I-Min A. Chen, N. Kyrpides, V. Markowitz, K. Palaniappan, N. Ivanova, N. Mikhailova, G. Ovchinnikova, E. Andersen, A. Pati, D. Stamatis, T.B.K. Reddy, N. Shapiro, H.P. Nordberg, M.N. Cantor, S. X. Hua, T. Woyke, and R. M. Kelly (2015). Complete genome sequences of Caldicellulosiruptor sp. strain Rt8.B8, Caldicellulosiruptor sp. strain Wai35.B1, and "Thermoanaerobacter cellulolyticus". Genome Announc. 3(3):e00440-15

Izquierdo, J.A. and K. Nüsslein (2015). Variation in diazotrophic community structure in forest soils reflects land use history. Soil Biol Biochem 80:1-8

Keller, M., A. Loder, M. Basen, J.A. Izquierdo, R.M. Kelly and M.W.W. Adams (2014). Production of lignofuels and electrofuels by extremely thermophilic microbes. Biofuels 5(5): 499-515

Izquierdo, J.A., S. Pattathil, A. Guseva, M.G. Hahn, L.R. Lynd (2014). Comparative analysis of the ability of Clostridium clariflavum strains and Clostridium thermocellum to utilize hemicellulose and unpretreated plant material. Biotechnology for Biofuels 7:136

Van Houdt, R., D. Van der Lelie, J.A. Izquierdo, A. Aertse, J. Masschelein, R. Lavigne, C.W. Michiels, S. Taghavi (2014). Genome sequence of Serratia plymuthica RVH1, isolate from a raw vegetable-processing line. Genome Announc. 2(1):e00021-14

Reed, PT., J.A. Izquierdo, L.R. Lynd (2014). Growth of Clostridium thermocellum and an environmental consortium in automated repetitive batch fermentation. Biores Biotechnol 155:50-56

Dykstra, A.B., L. St. Brice, M. Rodriguez, B. Raman, J.A. Izquierdo, K.D. Cook, L.R. Lynd, R.L. Hettich (2014). Development of a multi-point quantitation method to simultaneously measure enzymatic and structural components of the Clostridium thermocellum cellulosome protein complex. J Proteome Res 13(2):692-701

StBrice, L., X. Shao, J.A. Izquierdo, L.R. Lynd (2014). Optimization of affinity digestion for isolating cellulase from Clostridium thermocellum. Prep Biochem Biotechnol 44(2):206-216

Taghavi, S., J.A. Izquierdo, D. van der Lelie (2013). Complete genome sequence of Clostridium sp. DL-VIII, a novel solventogenic clostridium isolated from anaerobic sludge. Genome Announc 1(4):e00605-13

Li, L.L., S. Taghavi, J.A. Izquierdo, D. van der Lelie (2012). Complete genome sequence of Clostridium sp. strain BNL1100, a cellulolytic mesophile isolated from corn stover. J Bacteriol 194(24):6982-6983

Mearls E.B., J.A. Izquierdo, L.R. Lynd (2012). Formation and characterization of non-growth states in Clostridium thermocellum: spores and L-forms. BMC Microbiol 12:180

Izquierdo, J.A., L. Goodwin, K. Davenport, H. Teshima, D. Bruce, C. Detter, R.Tapia, S. Han, M. Land, L. Hauser, J. Han, S. Pitluck, M.Nolan, A. Chen, M. Huntemann, K.Mavromatis, N. Mikhailova, K. Liolios, T. Woyke, L.R. Lynd (2012). The complete genome of Clostridium clariflavum DSM 19732. Stand Genomic Sci 6(1):104-115

Sizova, M.V., J.A. Izquierdo, N. Panikov, and L.R. Lynd (2011). Thermophilic anaerobic bacteria from biocompost able to degrade cellulose and xylan. Appl Environ Microbiol 77(7):2282–2291

Izquierdo, J.A., M.V. Sizova, L.R. Lynd (2010). Diversity of bacteria and glycosyl hydrolase family 48 genes in cellulolytic consortia enriched from thermophilic biocompost. Appl Environ Microbiol 76(11): 3545-3553

Izquierdo, J.A. and K. Nüsslein (2006). Distribution of extensive nifH gene diversity across physical soil microenvironments. Microb Ecol 51(4): 441-452


Recent Courses Taught

Course Title Level
BIO 011 (NS) INTRO CELL BIO & GENETICS Undergraduate
BIO 025 GENERAL MICROBIOLOGY Undergraduate
BIO 093 INDPNDT STUDY -HONORS UG RES I Undergraduate
BIO 094 INDPNDT STUDY-HONORS UG RES II Undergraduate
BIO 143 MICROBIOLOGY Undergraduate
BIO 173 INTRO GENOMICS & BIOINFRMTCS Undergraduate
BIO 273 GENOMICS & BIOINFORMATICS Graduate
BIO 301 MASTERS THESIS 1 Graduate
BIO 302 MASTERS THESIS 2 Graduate
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